A study published in the journal ‘Life Science’ found that resistance exercise training improved multiple health related factors in breast cancer survivors who were treated with the drug Tamoxifen. Furthermore, it was found that even on stopping resistance training many of the positive effects obtained from training remained.
The present study aimed to assess the effects of resistance training and subsequent detraining on body composition, muscle strength, lipid profile, oxidative stress, and inflammatory markers among postmenopausal breast cancer survivors undergoing tamoxifen treatment.
For the purpose of this study, a total of 14 postmenopausal breast cancer survivors underwent 12-weeks of resistance exercise training followed by another 12-weeks of detraining. The participants of this study were measured using various metrics before starting resistance training and after the 24-week period consisting of training and subsequent detraining.
The results indicated a decrease in fat mass, triglycerides, total cholesterol and certain oxidative stress markers and an increase in muscle strength, and HDL cholesterol during the training period. Furthermore, many of these positive outcomes that were achieved from resistant training were maintained even after the 12-week period of detraining.
In conclusion, it was found that resistance exercise improves multiple health markers and a period of detraining by ceasing resistance training is not sufficient to reverse the positive effects obtained from training, especially with regards to oxidative stress markers.
Source: de Jesus Leite MAF, Mariano IM, Dechichi JGC, Giolo JS, Gonçalves ÁC, Puga GM. Exercise training and detraining effects on body composition, muscle strength and lipid, inflammatory and oxidative markers in breast cancer survivors under tamoxifen treatment. Life Sci. 2021 Nov 1;284:119924. Epub 2021 Sep 2. PMID: 34480935.
Source link: https://pubmed.ncbi.nlm.nih.gov/34480935/
Know the cancer – Breast cancer treatment
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